November 21, 2018
Recent Publications

  1. Laila A Abou-Zeid, Mohammed Hefnawy Molecular Modeling study of the Chiral Recognition of Celiprolol Enantiomers by a β- Cyclodextrin. The Pharmaceutical and Chemical Journal, 2015, 2(3):16-23 
  2. Laila A. Abouzeid, Hussein I. El-Subbagh DNA binding of Ethyl 2-substituted aminothiazole-4-carboxylate analogues: A molecular modeling approach to predict their antitumor activity; Future Journal of Pharmaceutical Sciences 2015, 1; 1-7.
  3. Deema A. Al-Turki, Mohamed A. Al-Omar, Laila A. Abou-zeid , Ihsan A. Shehata, Mohammed S. Al-Awady  Design, synthesis, molecular modeling and biological evaluation of novel diaryl heterocyclic analogs as potential selective cyclooxygenase-2 (COX-2) inhibitors Saudi Pharm J. 2015  doi:10.1016/j.jsps.2015.07.001
  4. Gerald M. Alter, Laila Abou-Zeid. Molecular Dynamic Simulation of Malate Dehydrogenase. SMU Medical Journal 2015; 2;  270-280.
  5. Tamer R. Kosbar,   Mamdouh A. Sofan,   Laila Abou-Zeid, Erik B. Pedersen Thermal stability of G-rich anti-parallel DNA triplexes upon insertion of LNA and α-L-LNA. Org. Biomol. Chem., 2015, 13; 5115.
  6. Morkos A. Henen, Laila Abou-Zeid, Alaa El-Din Barghash and Hassan Eisa. 19F-NMR as a powerful tool for measuring binding of synthesized small combinatorial dynamic library components with the armadillo repeat domain of human ß-catenin. Current Topics in Peptide & Protein R e s e a r c h 2014; 15: 35-39
  7. Sherin M. El-Feky, Laila A. Abou-Zeid, Mohamed A.  Massoud, Shady K. George and Hassan M. Eisa. Computational design, molecular modeling and synthesis of new 1,2,4-triazole analogs with potential antifungal activities.  SMU Medical Journal 2014, 1, 224 – 242
  8. Laila Abou-zeid, Hany N. Baraka. Combating oxidative stress as a hallmark of cancer & Aging: Computational modeling and Synthesis of phenylene diamine analogs as potential antioxidant.Saudi Pharm. J. 2014, 22(3): 264–272.
  9. Morkos A. Henen, Laila Abou-Zeid, Alaa El-Din Barghash and Hassan M. Eisa. Nuclear magnetic resonance as a breakthrough frontier in fragment-based drug design. JAS 2013; 9(11) 459-466.
  10. Tamer Kosbar, Mohamed Waly, Laila Abou-Zeid, Mamdouh Sofan, Jesper Wengel, Erik Pedersen. Highly Efficient Synthesis of Allopurinol LNA via C6 Deamination of 8-Aza-7-bromo-7-deazaadenine LNA. Synthesis,  2013, 45(23): 3259-3262
  11. Said M. Bayomi, Hassan A. El-Kashef, Mahmoud B. El-Ashmawy, Magda N. A. Nasr, Magda A. El-Sherbeny,  Farid A. Badria, Laila A. Abou-zeid,  Mariam A. Ghaly, Naglaa I. Abdel-Aziz.  Synthesis and biological evaluation of new curcumin derivatives as antioxidant and antitumor agents, Medicinal Chemistry Research 2013, 22(3), 1147-1162.
  12. Waleed A. Bayoumi, Magda A. Elsayed, Hany N. Baraka and Laila Abou-zeid. Computational Modeling, Synthesis and Antioxidant Potential of Novel Phenylcarbamoylbenzoic Acid Analogs in Combating Oxidative Stress. Archiv der Pharmazie 2012,  345, 902-910.
  13. Magda A.-A. El Sayed , Mohamed A. Massoud , Atif S. Tantawy, Magda N. A. Nasr, Alaa El-Dine M. Barghash, Laila A. Abou-Zeid Synthesis and biological evaluation of new unsaturated derivatives of cyclic compounds as potent antioxidant agent. Der Pharma Chemica, 2012, 4(5):1785-1797.
  14. Mohamed Attia Waly, Laila Abou-zeid, Sameh Ramadan El-Gogary, Mona Abbas Shalaby. One-pot Synthesis, Molecular Modeling and In Vitro Antibacterial Activity of Novel 3-(1,3,4-Oxadiazol-2-yl) Quinoxaline 1,4-Dioxide and Pyrazolyl Analogs Acta Chim. Slov.  . 2012,  59, 32–41
  15. Abdelbasset A. Farahat, David W. Boykin. Facile Synthesis of Aryl- Pyridyl, Pyridazinyl, Pyrazinyl and Triazinyl Acetonitriles. J. Heterocycl. Chem201350, 585-589.
  16. Bakr F. Abdel-Wahab, Hanan A. Mohamed, Abdelbasset A. Farahat, Seik Weng Ng and Edward R. T. Tiekinkc, 4-Dimethylamino-1-(4-methoxyphenyl)- 2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile, Acta Crystallographica2013, E69, o437.Munde, Manoj; Wang, Shuo; Kumar, Arvind; Stephens, Chad; Farahat, Abdelbasset; Boykin
  18. Manoj Munde, Arvind Kumar, Paul Peixoto, Sabine Depauw, Mohamed A. Ismail, Abdelbasset A. Farahat,  Ananya Paul, Martial V. Say,  Marie-Hélène David-Cordonnier, David W. Boykin, and W. David Wilson. The Unusual Monomer Recognition of Guanine-Containing Mixed Sequence DNA by a Dithiophene Heterocyclic Diamidine. Biochemistry, 2014, 53, 1218−1227.
  19. Abdelbasset A. Farahat, David W. Boykin. Copper (I) 3-Methylsalicylate, an efficient catalyst for N-arylation of heterocycles under moderate reaction conditions. Tetrahedron Letters2014, 55, 3049-3051.
  20. B. L. Timm, P. B. DA Silva, M. M. Batista, A. A. Farahat, A. Kumar, D. W. Boykin and M. N. C. Soeiro. In vitro investigation of the efficacy of novel diamidines against Trypanosoma cruziParasitology, 2014, 141, 1272-1276
  21. Abdelbasset A. Farahat, David W. Boykin. Copper (I) 3-Methylsalicylate mediates the Chan-Lam N-arylation of heterocycles, Synthetic Comm., 2015, 45, 245–252.
  22. Sarah Laughlin, Siming Wang, Abdelbasset A. Farahat, Arvind Kumar, David W. Boykin1, W. David Wilson. Resolution of mixed site DNA complexes with dimer-forming minor groove binders by using electrospray ionization mass spectrometry: Compound structure and DNA sequence effects, Chemistry A European Journal2015, 215528-5539.
  23. B. F. Abdel-Wahab, Rizk E. Khidre, Abdelbasset A. Farahat, H. A. Mohamed. Synthetic routes to Pyrazole-3(5)-carboxylates. J. Heterocycl. ChemAvailable online March 2015.
  24. Abdel-Wahab, B. F.; Mohamed, H. A.; Abdelbasset A. Farahat. Ethyl coumarin-3-carboxylate: synthesis and chemical properties. Org. Comm.  2014, 7, 1-27

  26. Ethyl Coumarin-3-Carboxylate: Synthesis and ChemicalPropertiesBakr F. Abdel-Wahab1*, Hanan A. Mohamed2 and Abdelbasset A. Farhat3*

  28. Optimization of Bipyridinyl Pyrazole Scaffolds via Design, Synthesis and Screening of a New Series of ROS1 Kinase-modulating Compounds Mohammad M. Al-Sanea,†,‡,k Byung Sun Park,§,k Ahmed Z. Abdelazem,†,‡ Khalid B. Selim, Kyung Ho Yoo,‡ Taebo Sim,‡ Jin Sung Tae,§ and So Ha Lee‡,*
  29. Enantioselective Ruthenium-Catalyzed 1,3-Dipolar Cycloadditions between C‑Carboalkoxy Ketonitrones and Methacrolein: Solvent Effect on Reaction Selectivity and Its Rational Khalid B. Selim,†,‡ Arnaud Martel,† Mathieu Y. Laurent,† Jérôme Lhoste,† Sandrine Py,§ and Gilles Dujardin*,† 
  30. Synthesis and antiviral activity of benzimidazolyland triazolyl-1,3,5-triazines Azza R. Maarouf • Abdelbasset A. Farahat •Khalid B. Selim • Hassan M. Eisa
  31. Organocatalytic enantio- and diastereoselective 1,3-dipolar cycloaddition between alanine-derived ketonitrones and E-crotonaldehyde: efficiency and full stereochemical studies Khalid B. Selim a,b, Anne Beauchard a, Jérôme Lhoste a, Arnaud Martel a, Mathieu Y. Laurent a,Gilles Dujardin a,⇑
  32. Steric tuning of C2-symmetric chiral N-heterocyclic carbene in gold catalyzed asymmetric cyclization of 1,6-enynes Ken-ichi Yamada a,*, Yasumasa Matsumoto a, Khalid B. Selim b, Yasutomo Yamamoto c, Kiyoshi Tomioka c,*
  33. Rhodium-catalyzed reductive cyclization of 1,6-enynes and stereoselective synthesis of the putative structure of lucentamycin A and its stereoisomers Young Jin Hama, Hana Yu a, Nam Doo Kim b, Jung-Mi Hah a, Khalid B. Selim a, Hwan Geun Choi a,Taebo Sim a,*
  34. Chiral carbene approach to gold-catalyzed asymmetric cyclization of 1,6-enynes Yasumasa Matsumoto, Khalid B. Selim, Hirotsugu Nakanishi, Ken-ichi Yamada, Yasutomo Yamamoto, Kiyoshi Tomioka *
  35. Stereoselective total synthesis of the E-isomer of putative lucentamycin A Khalid B. Selim, Baeck Kyoung Lee, Taebo Sim ⇑
  36. Peptidic Amidomonophosphane Ligand for Copper-Catalyzed Asymmetric Conjugate Addition of Diorganozincs to Cycloalkenones
  37. Efficient Chiral N-Heterocyclic Carbene/Copper(I)-Catalyzed Asymmetric Allylic Arylation with Aryl Grignard Reagents**Khalid B. Selim, Yasumasa Matsumoto, Ken-ichi Yamada, and Kiyoshi Tomioka*
  38. Amidophosphane–Copper(I)-Catalyzed Asymmetric Conjugate Addition of Dialkylzinc Reagents to Racemic 6-Substituted Cyclohexenones to Form 2,5-Di- and 2,2,5-Trisubstituted Cyclohexanones Khalid Selim, Takahiro Soeta, Ken-ichi Yamada, and Kiyoshi Tomioka*[a]
  39. Copper-catalyzed asymmetric allylic substitution with aryl and ethyl Grignard reagentsw Khalid B. Selim, Ken-ichi Yamada and Kiyoshi Tomioka*
  40. Chiral N-Heterocyclic Carbene-Copper(I)-Catalyzed Asymmetric Allylic Arylation of Aliphatic Allylic Bromides: Steric and Electronic Effects on γ-Selectivity Khalid B. Selim,† Hirotsugu Nakanishi,‡ Yasumasa Matsumoto,‡ Yasutomo Yamamoto,§ Ken-ichi Yamada,‡ and Kiyoshi Tomioka*,‡,§
  41. Kinetic Resolution of 5-Substituted Cycloalkenones by Peptidic Amidophosphane-Copper-Catalyzed Asymmetric Conjugate Addition of Dialkylzinc Authors: Takahiro Soeta, Khalid Selim, Masami Kuriyama, Kiyoshi Tomioka
  42. Peptidic Amidomonophosphane Ligand for Copper-Catalyzed Asymmetric Conjugate Addition of Diorganozincs to Cycloalkenones