Noura H. Abou-Taleb*, Nahed M. El-Enany, Dina T. El-Sherbiny, & Hussein I. El-Subbagh. Spider diagram and Analytical GREEnness metric approach for assessing the greenness of quantitative 1H-NMR determination of lamotrigine: Taguchi method based optimization. Chemometrics and Intelligent Laboratory Systems 2021, 209, 104198. https://doi.org/10.1016/J.CHEMOLAB.2020.104198

Mohamed A. Abu El-Enin, Yomna A. Salem, Saadia M. El-Ashry, and Mohammed E. A. Hammouda. Applying eco-friendly micellar liquid chromatography for the simultaneous determination of two ternary mixtures utilized for cold treatment using monolithic column. Journal of the Chinese Chemical Society 2021, 68(9), 1686–1696. https://doi.org/10.1002/JCCS.202100093

Amal A. El-Masry, Dalia R. El-Wasseef, Manal Eid, Ihsan A. Shehata, and Abdallah M. Zeid. Quantitative proton nuclear magnetic resonance method for simultaneous analysis of fluticasone propionate and azelastine hydrochloride in nasal spray formulation. Royal Society Open Science 2021, 8(7). https://doi.org/10.1098/RSOS.210483

Amal A. El-Masry, Dalia R. El-Wasseef, Manal Eid, Ihsan A. Shehata, and Abdallah M. Zeid. Optimization and Validation of a Facile RP-HPLC Method for Determination of Betrixaban and Lercanidipine in Pharmaceutical and Biological Matrices. Journal of Chromatographic Science 2021, 59(8), 785–794. https://doi.org/10.1093/CHROMSCI/BMAB088

Amal A. El-Masry, Abdallah M. Zeid, Dalia R. El-Wasseef, Manal Eid, and Ihsan A. Shehata.  A Validated Quantitative ¹H Nuclear Magnetic Resonance (¹H-qNMR) Method for Quantification of a Novel Anti-Coagulant Drug (Betrixaban Maleate) with Assessing Its Stability by Application to Degradation Study. Analytical Chemistry Letters 2021, 10(6), 768–783. https://doi.org/10.1080/22297928.2021.1875873

Noura M. Mansour, Dina T. El-Sherbiny, Fawzia A. Ibrahim, and Hussein I. El Subbagh.  Development of an Inexpensive, sensitive and green HPLC method for the simultaneous determination of brivaracetam, piracetam and carbamazepine; application to pharmaceuticals and human plasma. Microchemical Journal 2021, 163, 105863. https://doi.org/10.1016/J.MICROC.2020.105863

Nataliia Shulyak, Marjan Piponski, Sergiy Kovalenko, Tanja B. Stoimenova, Trajan Balkanov, Hussein I. El-Subbagh, Iryna Drapak, Joy O. Omotosho, and Liliya Logoyda.  Development of a Novel, Fast, Simple HPLC Method for Determination of Atorvastatin and its Impurities in Tablets. Scientia Pharmaceutica 2021, 89(2), 16. https://doi.org/10.3390/SCIPHARM89020016

Mary E. Wahba, Dalia R. El Wasseef,   Ahmed S. Saad*  &  Mohammed E. Draz   Calixarene based portable sensor for the direct assay of indiscriminate ephedrine content of weight loss herbal preparations. RSC Advances 2021, 11(21), 12833–12844. https://doi.org/10.1039/D0RA10254G

Mary E. Wahba, Dalia R. El Wasseef & Dina T. El Sherbiny.  Studying the suitability of hybrid micelle liquid chromatography for estimating the lipophilicity of some partial dopamine agonists used to attain the reward circuit. Royal Society Open Science 2021, 8(5). https://doi.org/10.1098/RSOS.202371

Mary E. Wahba, Dina T. El Sherbiny, & Dalia R. El Wasseef.  Estimating chiral selector potential of micelle-based mobile phases through the analysis of some enantiomeric mixtures. Journal of Taibah University for Science 2021, 15(1), 145–153. https://doi.org/10.1080/16583655.2021.1927399

Ashraf N. Abdalla, Miriana D. Stefano, Giulio Poli, Tiziano Tuccinardi, Ammar Bader, Antonio Vassallo, Mohamed E. Abdallah, Mahmoud Z. El-Readi, Bassem Refaat, Alanood S. Algarni, Rizwan Ahmad, Hamad M. Alkahtani, Alaa A. M. Abdel-Aziz, Adel S. El-Azab, and Aljawharah Alqathama. Co-Inhibition of P-gp and Hsp90 by an Isatin-Derived Compound Contributes to the Increase of the Chemosensitivity of MCF7/ADR-Resistant Cells to Doxorubicin. Molecules 2021, 27(1). https://doi.org/10.3390/MOLECULES27010090

Alaa A. M. Abdel-Aziz, Adel S. El-Azab, Nawaf A. AlSaif, Ahmad J. Obaidullah, Abdulrahman M. Al-Obaid, and Ibrahim A. Al-Suwaidan. Synthesis, potential antitumor activity, cell cycle analysis, and multitarget mechanisms of novel hydrazones incorporating a 4-methylsulfonylbenzene scaffold: a molecular docking study. Journal of Enzyme Inhibition and Medicinal Chemistry 2021, 36(1), 1521–1539. https://doi.org/10.1080/14756366.2021.1924698/SUPPL_FILE/IENZ_A_1924698_SM5087.PDF

Mohammed S. Abdel-Maksoud, Mohammed I. El-Gamal, Bong S. Lee, Mahmoud M. Gamal El-Din, Hong R. Jeon, Dow Kwon, Usama M. Ammar, Karim I. Mersal, Eslam M. H. Ali, Kyung T. Lee, Kyung H. Yoo, Dong K. Han, Jae K. Lee, Garam Kim, Hong S. Choi, Young J. Kwon, Kwan H. Lee, and Chang H. Oh. Discovery of New Imidazo[2,1- b]thiazole Derivatives as Potent Pan-RAF Inhibitors with Promising In Vitro and In Vivo Anti-melanoma Activity. Journal of Medicinal Chemistry 2021, 64(10), 6877–6901. https://doi.org/10.1021/ACS.JMEDCHEM.1C00230

Somaya A. Abdel-Rahman, Emad I. Wafa, Kareem Ebeid, Sean M. Geary, Youssef W. Naguib, Ashraf K. El-Damasy, Aliasger K. Salem. Thiophene Derivative-Loaded Nanoparticles Mediate Anticancer Activity Through the Inhibition of Kinases and Microtubule Assembly. Advanced Therapeutics 2021, 4(7), 2100058. https://doi.org/10.1002/ADTP.202100058

Mennatallah M. Abdelshaheed, Iten M. Fawzy, Hussein I. El-Subbagh, and Khairia M.Youssef. Piperidine nucleus in the field of drug discovery. Future Journal of Pharmaceutical Sciences 2021 7:1, 7(1), 1–11. https://doi.org/10.1186/S43094-021-00335-Y

Dhulfiqar A. Abed, Sumi Lee, Xia Wen, Ahmed R. Ali, Vaibhav Mangipudy, Lauren M. Aleksunes, and Longqin Hu.  Optimization of 1,4-bis(arylsulfonamido)naphthalene-N,N’-diacetic acids as inhibitors of Keap1-Nrf2 protein-protein interaction to suppress neuroinflammation. Bioorganic & Medicinal Chemistry 2021, 44. https://doi.org/10.1016/J.BMC.2021.116300

Youssef Aboushady, Moustafa T. Gabr, Ahmed K. Elhady, Mohamed Salah, Ashraf H. Abadi, Gerrit Wilms, Walter Becker, Mohammad Abdel-Halim, and Matthias Engel. Discovery of Hydroxybenzothiazole Urea Compounds as Multitargeted Agents Suppressing Major Cytotoxic Mechanisms in Neurodegenerative Diseases. ACS Chemical Neuroscience 2021, 12(22), 4302–4318. https://doi.org/10.1021/ACSCHEMNEURO.1C00475

Hatem A. Abuelizz, Saied M. Soliman, Hazem A. Ghabbour, Mohamed Marzouk, Mohamed M. Abdellatif, and Rashad Al-Salahi. DFT Calculation, Hirshfeld Analysis and X-Ray Crystal Structure of Some Synthesized N-alkylated (S-alkylated)-[1,2,4] triazolo[1,5-a]quinazolines. Crystals 2021, 11(10), 1195. https://doi.org/10.3390/CRYST11101195

Hanan A. Al-Ghulikah, Aamal A. Al-Mutairi, Hanan M. Hassan, Ali A. Emam, Y. Sheena Mary, Y. Shyma Mary, Stevan Armaković, and Sanja J. Armaković. Reactivity properties and adsorption behavior of a triazole derivative – DFT and MD simulation studies. Journal of Molecular Liquids 2021, 341, 117439. https://doi.org/10.1016/J.MOLLIQ.2021.117439

Abdullah M. Al-Majid, Saied M. Soliman, Hazem A. Ghabbour, M. Ali, Mohammad S. Islam, Mohammed R. Shaik, and Assem Barakat. Synthesis and X-ray crystal structure of unexpected novel thiazolidinone/1,3,4-thiadiazole heterocycle via S-alkylation and Smiles rearrangement dual approaches. Journal of Molecular Structure 2021, 1234, 130156. https://doi.org/10.1016/J.MOLSTRUC.2021.130156

Aamal A. Al-Mutairi, Kowsalya Alagappan, Olivier Blacque, Monirah A. Al-Alshaikh, Ali A. El-Emam, M. Judith Percino, and Subbiah Thamotharan. Crystallographic and Theoretical Exploration of Weak Hydrogen Bonds in Arylmethyl N′-(adamantan-1-yl) piperidine-1-carbothioimidates and Molecular Docking Analysis. ACS Omega 2021, 6(41), 27026–27037. https://doi.org/10.1021/ACSOMEGA.1C03559

Mohyeddine Al-Qubati, Hazem A. Ghabbour, Saied M. Soliman, Eman Alzahrani, and Mujeeb A. Sultan. X-ray and computational investigations of ethanoanthracenes: 9,10-dihydro-9,10-ethanoanthracene-12-carboxylic acid and 9,10-dihydro-9,10-ethanoanthracen-9-yl)-N-methylethanamine. Molecular Crystals and Liquid Crystals 2021, https://doi.org/10.1080/15421406.2021.2008173

Mohammad M. Al-Sanea, Garri Chilingaryan, Narek Abelyan, Arsen Sargsyan, Sargis Hovhannisyan, Hayk Gasparyan, Smbat Gevorgyan, Sarah Albogami, Mohammed M. Ghoneim, Ahmed K. Farag, Ahmed A. B. Mohamed, and Ashraf K. El-Damasy. Identification of novel potential vegfr-2 inhibitors using a combination of computational methods for drug discovery. Life 2021, 11(10). https://doi.org/10.3390/LIFE11101070/S1

Majed J. Al-wadei, Ahmed H. Bakheit, Alaa A. M. Abdel-Aziz, and Tanveer A. Wani. Betaxolol: A comprehensive profile. Profiles of Drug Substances, Excipients and Related Methodology 2021, 46, 91–136. https://doi.org/10.1016/BS.PODRM.2020.07.002

Lamya H. Al-Wahaibi, Sai R, S. Bysani, Samar S. Tawfik, Mohammed S. M. Abdelbaky, Santiago Garcia-Granda, Ali A. El-Emam, M. Judith Percino, and Subbiah Thamotharan.  Invariant and Variable Supramolecular Self-Assembly in 6-Substituted Uracil Derivatives: Insights from X-ray Structures and Quantum Chemical Study. Crystal Growth and Design 2021, 21(6), 3234–3250. https://doi.org/10.1021/ACS.CGD.0C01583

Lamya H. Al-Wahaibi, Divya S. Grandhi, Samar S. Tawfik, Nora H. Al-Shaalan, Mohammed A. Elmorsy, Ali A. El-Emam, M. Judith Percino, and Subbiah Thamotharan. Probing the Effect of Halogen Substituents (Br, Cl, and F) on the Non-covalent Interactions in 1-(Adamantan-1-yl)-3-arylthiourea Derivatives: A Theoretical Study. ACS Omega 2021, 6(7), 4816–4830. https://doi.org/10.1021/acsomega.0c05793

Lamya H. Al-Wahaibi, Ahmed A. B. Mohamed, Samar S. Tawfik, Hanan M. Hassan, and Ali A. El-Emam. 1,3,4-Oxadiazole N-Mannich Bases: Synthesis, Antimicrobial, and Anti-Proliferative Activities. Molecules 2021, 26(8), 2110. https://doi.org/10.3390/MOLECULES26082110

Lamya H. Al-Wahaibi, Bavanandan Rahul, Ahmed A. B. Mohamed, Mohammed S. M. Abdelbaky, Santiago Garcia-Granda, Ali A. El-Emam, M. Judith Percino, and Subbiah Thamotharan.  Supramolecular Self-Assembly Built by Weak Hydrogen, Chalcogen, and Unorthodox Nonbonded Motifs in 4-(4-Chlorophenyl)-3-[(4-fluorobenzyl) sulfanyl]-5-(thiophen-2-yl)-4 H-1,2,4-triazole, a Selective COX-2 Inhibitor: Insights from X-ray and Theoretical Studies. ACS Omega 2021, 6(10), 6996–7007. https://doi.org/10.1021/acsomega.0c06287

Lamya H. Al-Wahaibi, Althaf Shaik, Mohammed A. Elmorsy, Mohammed S. M. Abdelbaky, Santiago Garcia-Granda, Subbiah Thamotharan, Vijay Thiruvenkatam, and Ali A. El-Emam.  Structural Insights of Three 2,4-Disubstituted Dihydropyrimidine-5-carbonitriles as Potential Dihydrofolate Reductase Inhibitors. Molecule 2021, 26(11). https://doi.org/10.3390/MOLECULES26113286

Eslam M. H. Ali, Rania Farag A. El-Telbany, Mohammed S. Abdel-Maksoud, Usama M. Ammar, Karim I. Mersal, Seyed O. Zaraei, Mohammed I. El-Gamal, Se I. Choi, Kyung T. Lee, Hee K. Kim, Kwan H. Lee, and Chang H. Oh.  Design, synthesis, biological evaluation, and docking studies of novel (imidazol-5-yl) pyrimidine-based derivatives as dual BRAF V600E/p38α inhibitors. European Journal of Medicinal Chemistry 2021, 215. https://doi.org/10.1016/J.EJMECH.2021.113277

Abdulrhman Alsayari, Abdullatif Bin Muhsinah, Yahya I. Asiri, Faiz A. Al-Aizari, Nabila A. Kheder, Zainab M. Almarhoon, Hazem A. Ghabbour, and Yahia N. Mabkhot.  Synthesis, Characterization, and Biological Evaluation of Some Novel Pyrazolo[5,1-b] thiazole Derivatives as Potential Antimicrobial and Anticancer Agents. Molecules 2021, 26(17), 5383. https://doi.org/10.3390/MOLECULES26175383

Hanan S. Anbar, Zahraa Isa, Jana J. Elounais, Mariam A. Jameel, Joudi H. Zib, Aya M. Samer, Aya F. Jawad, and Mohammed I. El-Gamal.  Steroid sulfatase inhibitors: the current landscape. Expert Opinion on Therapeutic Patents 2021, 31(6), 453–472. https://doi.org/10.1080/13543776.2021.1910237

Yahya I. Asiri, Abdullatif Bin Muhsinah, Abdulrhman Alsayari, Hazem A. Ghabbour, Zainab M. Almarhoon, Faiz A. Al-aizari, Kumar Venkatesan, Syed Tasqeeruddin, Syeda S. Sulthana, and Yahia N. Mabkhot.  Design, synthesis, X-ray analysis, and biological screening of new oxime and enaminone thiazoline-2-thione derivatives. Journal of Molecular Structure 2021, 1223, 128977. https://doi.org/10.1016/J.MOLSTRUC.2020.128977

Amr El-Demerdash, Ahmed A. Al-Karmalawy, Tarek M. Abdel-Aziz, Sameh S. Elhady, Khaled M. Darwish, and Ahmed H. E. Hassan.  Investigating the structure–activity relationship of marine natural polyketides as promising SARS-CoV-2 main protease inhibitors. RSC Advances 2021, 11(50), 31339–31363. https://doi.org/10.1039/D1RA05817G

Mahmoud M. Gamal El-Din, Mohammed I. El-Gamal, Young D. Kwon, Su Y. Kim, Hee S. Han, Sang E. Park, Chang H. Oh, Kyung T. Lee, and Hee K. Kim.  Evaluation of the Inhibitory Effects of Pyridylpyrazole Derivatives on LPS-Induced PGE2 Productions and Nitric Oxide in Murine RAW 264.7 Macrophages. Molecules 2021, 26(21). https://doi.org/10.3390/MOLECULES26216489

Mohammed I. El-Gamal, Nada H. Mewafi, Nada E. Abdelmotteleb, Minnatullah A. Emara, Hamadeh Tarazi, Rawan M. Sbenati, Moustafa M. Madkour, Seyed O. Zaraei, Afnan I. Shahin, and Hanan S. Anbar.  A Review of HER4 (ErbB4) Kinase, Its Impact on Cancer, and Its Inhibitors. Molecules 2021, 26(23). https://doi.org/10.3390/MOLECULES26237376

Hussein I. El-Subbagh, Novel GABA A Agonist Entities: Pharmacological Investigation and Molecular Modeling Study of Thiazolo- and Thiadiazolo-[3,2-a][1,3]diazepine Analogs. Mini Reviews in Medicinal Chemistry 2021, 21(9), 1048–1057. https://doi.org/10.2174/1389557521999201230195733

Hussein I. El-Subbagh, and Mohamed A. Sabry.  2-Substituted-mercapto-quinazolin-4(3H)-ones as DHFR Inhibitors. Mini-Reviews in Medicinal Chemistry 2021, 21(16), 2249–2260. https://doi.org/10.2174/1389557521666210304105736

Ahmed Elkamhawy, Sora Paik, Jong H. Park, Hyeon J. Kim, Ahmed H. E. Hassan, Kyeong Lee, Ki D. Park, and Eun J. Roh.  Synthesis, Cytotoxic Activity, Crystal Structure, DFT Studies and Molecular Docking of 3-Amino-1-(2,5-dichlorophenyl)-8-methoxy-1H-benzo[f]chromene-2-carbonitrile. Crystals 2021, 11(2), 184. https://doi.org/10.3390/CRYST11020184

Hoda A. Elkot, Ibrahim Ragab, Noha M. Saleh, Mohamed N. Amin, Sara T. Al-Rashood, Shahenda M. El-Messery, and Ghada S. Hassan.  Discovery of novel and potent safinamide-based derivatives as highly selective hMAO-B inhibitors for treatment of Parkinson’s disease (PD): Design, synthesis, in vitro, in vivo and in silico biological studies. Bioorganic Chemistry 2021, 115, 105233. https://doi.org/10.1016/J.BIOORG.2021.105233

Hoda A. Elkot, Ibrahim Ragab, Noha M. Saleh, Mohamed N. Amin, Sara T. Al-Rashood, Shahenda M. El-Messery, and Ghada S. Hassan.  Design, synthesis, and antitumor activity of PLGA nanoparticles incorporating a discovered benzimidazole derivative as EZH2 inhibitor. Chemico-Biological Interactions 2021, 344. https://doi.org/10.1016/J.CBI.2021.109530

Muhammed H. Elnaggar, Abdelrahman I. Abushouk, Ahmed H. E. Hassan, Hadeer M. Lamloum, Amira Benmelouka, Shurouk A. Moatamed, Hossam Abd-Elmegeed, Somia Attia, Aya Samir, Nouran Amr, Dina Johar, and Samy Zaky.  Nanomedicine as a putative approach for active targeting of hepatocellular carcinoma. Seminars in Cancer Biology 2021, 69, 91–99. https://doi.org/10.1016/J.SEMCANCER.2019.08.016

Menna A. Ewida, Heba A. Ewida, Mahmoud S. Ahmed, Heba A. Allam, Ramzia I. ElBagary, Riham F. George, Hanan H. Georgey, and Hussein I. El-Subbagh. 3-Methyl-imidazo[2,1-b] thiazole derivatives as a new class of antifolates: Synthesis, in vitro/in vivo bio-evaluation and molecular modeling simulations. Bioorganic Chemistry 2021, 115. https://doi.org/10.1016/J.BIOORG.2021.105205

Menna A. Ewida, Heba A. Ewida, Mahmoud S. Ahmed, Heba A. Allam, Ramzia I. ElBagary, Riham F. George, Hanan H. Georgey, and Hussein I. El-Subbagh. Nanomolar potency of imidazo[2,1-b] thiazole analogs as indoleamine 2,3-dioxygenase inhibitors. Archiv Der Pharmazie 2021, 354(11). https://doi.org/10.1002/ARDP.202100202

Salma Fares, Khalid B. Selim, Fatma E. Goda, Magda A. A. El-Sayed, Nawaf A. AlSaif, Mohamed M. Hefnawy, Alaa A. M. Abdel-Aziz, and Adel S. El-Azab.  Design, synthesis, and analysis of antiproliferative and apoptosis-inducing activities of nitrile derivatives containing a benzofuran scaffold: EGFR inhibition assay and molecular modelling study. Journal of Enzyme Inhibition and Medicinal Chemistry 2021, 36(1), 1488–1499. https://doi.org/10.1080/14756366.2021.1946044

Moustafa T. Gabr, Giuseppe Deganutti, and Christopher A. Reynolds.  Peptidomimetic-based approach toward inhibitors of microbial trimethylamine lyases. Chemical Biology & Drug Design 2021, 97(2), 231–236. https://doi.org/10.1111/CBDD.13775

Hyo S. Gil, Jeong H. Lee, Ahmed K. Farag, Ahmed H. E. Hassan, Kyung S. Chung, Jung H. Choi, Eun J.Roh, and Kyung T. Lee.  AKF-D52, a Synthetic Phenoxypyrimidine-Urea Derivative, Triggers Extrinsic/Intrinsic Apoptosis and Cytoprotective Autophagy in Human Non-Small Cell Lung Cancer Cells. Cancers 2021, 13(22). https://doi.org/10.3390/CANCERS13225849

Ahmed H. E. Hassan, Trong N. Phan, Seolmin Yoon, Cheol J. Lee, Hye R. Jeon, Seung H. Kim, Joo H. No, and Yong S. Lee.  Pyrrolidine-based 3-deoxysphingosylphosphorylcholine analogs as possible candidates against neglected tropical diseases (NTDs): identification of hit compounds towards development of potential treatment of Leishmania donovani. Journal of Enzyme Inhibition and Medicinal Chemistry 2021, 36(1), 1922–1930. https://doi.org/10.1080/14756366.2021.1969385

Hanan M. Hassan, Lamya H. Al-Wahaibi, George SG Shehatou, and Ali A. El-Emam.  Adamantane-linked isothiourea derivatives suppress the growth of experimental hepatocellular carcinoma via inhibition of TLR4-MyD88-NF-κB signaling. American Journal of Cancer Research 2021, 11(2), 350. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868765/

Aya Y. Hemaida, Ghada S. Hassan, Azza R. Maarouf, Jacques Joubert, and Ali A. El-Emam.  Synthesis and Biological Evaluation of Thiazole-Based Derivatives as Potential Acetylcholinesterase Inhibitors. ACS Omega 2021, 6(29), 19202–19211. https://doi.org/10.1021/ACSOMEGA.1C02549

Tarek S. Ibrahim, Ahmad J. Almalki, Amr H. Moustafa, Rasha M. Allam, Gamal El Din A. Abuo-Rahma, Hussein I. El Subbagh, and Mamdouh F. A. Mohamed.  Novel 1,2,4-oxadiazole-chalcone/oxime hybrids as potential antibacterial DNA gyrase inhibitors: Design, synthesis, ADMET prediction and molecular docking study. Bioorganic Chemistry 2021, 111. https://doi.org/10.1016/J.BIOORG.2021.104885

Jelena Đ. Jovanović, Marko Antonijević, Ali A. El-Emam, and Zoran Marković.  Comparative MD Study of Inhibitory Activity of Opaganib and Adamantane-Isothiourea Derivatives toward COVID-19 Main Protease M pro. ChemistrySelect 2021, 6(33), 8603–8610. https://doi.org/10.1002/SLCT.202101898

Khalid Karrouchi, Saad Fettach, El Hassane Anouar, Burak Tüzün, Smaail Radi, Abdulrahman I. Alharthi, Hazem A. Ghabbour, Yahia N. Mabkhot, My E. Faouzi, M’hammed Ansar, and Yann Garcia.  Synthesis, crystal structure, DFT, α-glucosidase and α-amylase inhibition and molecular docking studies of (E)-N’-(4-chlorobenzylidene)-5-phenyl-1H-pyrazole-3-carbohydrazide. Journal of Molecular Structure 2021, 1245, 131067. https://doi.org/10.1016/J.MOLSTRUC.2021.131067

Menna El Gaafary, Tatiana Syrovets, Hany M. Mohamed, Ahmed A. Elhenawy, Ahmed M. El-Agrody, Abd El Galil E. Amr, Hazem A. Ghabbour, and Abdulrahman A. Almehizia. 2021.Synthesis, Cytotoxic Activity, Crystal Structure, DFT Studies and Molecular Docking of 3-Amino-1-(2,5-Dichlorophenyl)-8-Methoxy-1H-Benzo[f]Chromene-2-Carbonitrile. Crystals 2021, 11(2):184. https://doi.org/10.3390/cryst11020184

Kun W. Lee, Ahmed H. E. Hassan, Youngdo Jeong, Seolmin Yoon, Seung H. Kim, Cheol J. Lee, Hye R. Jeon, Suk W. Chang, Ji Y. Kim, Dae S. Jang, Hee J. Kim, Jae H. Cheong, and Yong S. Lee Enantiopure methoxetamine stereoisomers: chiral resolution, conformational analysis, UV-circular dichroism spectroscopy and electronic circular dichroism. New Journal of Chemistry 2021, 45(9), 4354–4364. https://doi.org/10.1039/D0NJ05192F

Moustafa M. Madkour, Hanan S. Anbar, and Mohammed I. El-Gamal.  Current status and future prospects of p38α/MAPK14 kinase and its inhibitors. European Journal of Medicinal Chemistry 2021, 213. https://doi.org/10.1016/J.EJMECH.2021.113216

Shoaib Manzoor, Moustafa T. Gabr, Bisma Rasool, Kavita Pal, and Nasimul Hoda.  Dual targeting of acetylcholinesterase and tau aggregation: Design, synthesis and evaluation of multifunctional deoxyvasicinone analogues for Alzheimer’s disease. Bioorganic Chemistry 2021, 116, 105354. https://doi.org/10.1016/J.BIOORG.2021.105354

Shoaib Manzoor, Santosh K.Prajapati, Shreyasi Majumdar, Kausar Raza, Moustafa T. Gabr, Shivani Kumar, Kavita Pal, Haroon Rashid, Suresh Kumar, Sairam Krishnamurthy, and Nasimul Hoda.  Discovery of new phenyl sulfonyl-pyrimidine carboxylate derivatives as the potential multi-target drugs with effective anti-Alzheimer’s action: Design, synthesis, crystal structure and in-vitro biological evaluation. European Journal of Medicinal Chemistry 2021, 215, 113224. https://doi.org/10.1016/J.EJMECH.2021.113224

Michael K. Schultz, Christopher Pigge, Mengshi Li, Moustafa T. Gabr, Edwin Sagastume.  Compositions for chelating metals at low temperatures (Patent No. 17051037), 2021. https://pubchem.ncbi.nlm.nih.gov/patent/WO-2019240884-A3

Youssef W. Naguib, Sanjib Saha, Jessica M. Skeie, Timothy Acri, Kareem Ebeid, Somaya Abdel-rahman, Sandeep Kesh, Gregory A. Schmidt, Darryl Y. Nishimura, Jeffrey A. Banas, Min Zhu, Mark A. Greiner, and Aliasger K. Salem.  Solubilized ubiquinol for preserving corneal function. Biomaterials 2021, 275. https://doi.org/10.1016/J.BIOMATERIALS.2021.120842

Doaa A. Osman, Mario A. Macías, Lamya H. Al-Wahaibi, Nora H. Al-Shaalan, Luke S. Zondagh, Jacques Joubert, Santiago Garcia-Granda, and Ali A. El-Emam.  Structural Insights and Docking Analysis of Adamantane-Linked 1,2,4-Triazole Derivatives as Potential 11β-HSD1 Inhibitors. Molecules 2021, 26(17), 5335. https://doi.org/10.3390/MOLECULES26175335

Ashfaq Ur Rehman, Guodong Zhen, Bozitao Zhong, Duan Ni, Jiayi Li, Abdul Nasir, Moustafa T. Gabr, Humaira Rafiq, Abdul Wadood, Shaoyong Lu, Jian Zhang, and Hai Feng Chen.  Mechanism of zinc ejection by disulfiram in nonstructural protein 5A. Physical Chemistry Chemical Physics 2021, 23(21), 12204–12215. https://doi.org/10.1039/D0CP06360F

Adel S. El-Azab*, Nasr Y. Khalil, and Alaa A. M. Abdel-Aziz. Remarkable Conversion of 2-Thioxo-2,3-dihydroquinazolin-4(1H)-ones into the Corresponding Quinazoline-2,4(1H,3H)-diones: Spectroscopic Analysis and X-Ray Crystallography. Journal of Chemistry 2021, 2021. https://jglobal.jst.go.jp/en/detail?JGLOBAL_ID=202102241044633388

Sanjib Saha, Youssef W. Naguib, Jessica M. Skeie, Timothy Acri, Kareem Ebeid, Somaya Abdel-rahman, Sandeep Kesh, Gregory Schmidt, Darryl Y. Nishimura, Mark A. Greiner, and Aliasger K. Salem.  Solubilized Ubiquinol Improves Reactive Oxygen Species Scavenging in Donor Corneal Endothelial Cells. Investigative Ophthalmology & Visual Science 2021, 62(8), 834–834. https://pubmed.ncbi.nlm.nih.gov/34087583/

Rawan M. Sbenati, Mohammad H. Semreen, Ahlam M. Semreen, Mahmoud K. Shehata, Fai M. Alsaghir, and Mohammed I. El-Gamal.  Evaluation of imidazo[2,1-b] thiazole-based anticancer agents in one decade (2011-2020): Current status and future prospects. Bioorganic & Medicinal Chemistry 2021, 29. https://doi.org/10.1016/J.BMC.2020.115897

Rawan M. Sbenati, Seyed O. Zaraei, Mohammed I. El-Gamal, Hanan S. Anbar, Hamadeh Tarazi, Malaka M. Zoghbor, Najma A. Mohamood, Mahta M. Khakpour, Dana M. Zaher, Hany A. Omar, Nour N. Alach, Mahmoud K. Shehata, and Randa El-Gamal.  Design, synthesis, biological evaluation, and modeling studies of novel conformationally-restricted analogues of sorafenib as selective kinase-inhibitory antiproliferative agents against hepatocellular carcinoma cells. European Journal of Medicinal Chemistry 2021, 210. https://doi.org/10.1016/J.EJMECH.2020.113081

Mujeeb A. Sultan, Hazem A. Ghabbour, Saied M. Soliman, Renjith R. Pillai, and Mansour S. A. Galil.  Synthesis, Hirshfeld Surface Analysis and DFT Studies of Ethano-tetracyclic Tetracene Derivatives. Journal of Chemical Crystallography 2021, 51(2), 196–204. https://doi.org/10.1007/S10870-020-00841-6/FIGURES/8

Saif Ullah, Mohammed I. El-Gamal, Randa El-Gamal, Julie Pelletier, Jean Sévigny, Mahmoud K. Shehata, Hanan S. Anbar, and Jamshed Iqbal. Synthesis, biological evaluation, and docking studies of novel pyrrolo[2,3-b] pyridine derivatives as both ectonucleotide pyrophosphatase/phosphodiesterase inhibitors and antiproliferative agents. European Journal of Medicinal Chemistry 2021, 217. https://doi.org/10.1016/J.EJMECH.2021.113339

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