الهدف الرئيسى لجائزة مصر للتميز الحكومى السنوية هو تحفيز روح التنافس والتميز على مستوى الموظفين من جهة، وعلى مستوى المؤسسات الحكومية من جهة أخرى. ويتم تكريم المتميزين في أداء الخدمات العامة تكريماً معنوياً ومادياً مما يرسخ قيم العطاء والانتماء والتميز، ويحفز الجميع على الارتقاء بمستويات الأداء والالتزام بمعايير الجودة والتميز.

جائزة مصر للتميز الحكومى

Pharmacology and toxicology Publications 2019

 

  • Abdelmageed ME, Shehatou GS, Abdelsalam RA, Suddek GM, Salem HA. Cinnamaldehyde ameliorates STZ-induced rat diabetes through modulation of IRS1/PI3K/AKT2 pathway and AGEs/RAGE interaction. Naunyn-Schmiedebergs Archives of Pharmacology. 2019; 392(2):243-258. https://doi.org/10.1007/s00210-018-1583-4
  • Heikal MM1, Shaaban AA, Elkashef WF, Ibrahim TM. Effect of febuxostat on biochemical parameters of hyperlipidemia induced by a high-fat diet in rabbits. Can J Physiol Pharmacol. 2019; 97(7):611-622. https://doi.org/10.1139/cjpp-2018-0731
  • El-Sonbaty YA, Suddek GM, Megahed N, Gameil NM. Protocatechuic acid exhibits hepatoprotective, vasculoprotective, antioxidant and insulin-like effects in dexamethasone-induced insulin-resistant rats. Biochimie. 2019. pii: S0300-9084(19)30269-X. https://doi.org/10.1016/j.biochi.2019.09.011
  • Abdel-Dayem MA, Shaker ME, Gameil NM. Impact of interferon β-1b, interferon β-1a and fingolimod therapies on serum interleukins-22, 32α and 34 concentrations in patients with relapsing-remitting multiple sclerosis. J Neuroimmunol. 2019; 337:577062. https://www.sciencedirect.com/science/article/pii/S0165572819301845
  • Shawky NM, Shehatou GSG, Suddek GM, Gameil NM. Comparison of the effects of sulforaphane and pioglitazone on insulin resistance and associated dyslipidemia, hepatosteatosis, and endothelial dysfunction in fructose-fed rats. Environ ToxicolPharmacol. 2019; 66:43-54.       https://doi.org/10.1016/j.etap.2018.12.008
  • Khodir AE, Said E, Atif H, ElKashef HA, Salem HA. Targeting Nrf2/HO-1 signaling by crocin: Role in attenuation of AA-induced ulcerative colitis in rats. Biomed Pharmacother. 2019; 110:389-399. https://doi.org/10.1016/j.biopha.2018.11.133
  • Zaghloul MS, Said E, Suddek GM, Salem HA. Crocin attenuates lung inflammation and pulmonary vascular dysfunction in a rat model of bleomycin-induced pulmonary fibrosis. Life Sci. 2019; 235:116794. https://doi.org/10.1016/j.lfs.2019.116794
  • Nazmy EA, El-Khouly OA, Zaki MMA, Elsherbiny NM, Said E, Al-Gayyar MMH, Salem HA. Targeting p53/TRAIL/caspase-8 signaling by adiponectin reverses thioacetamide-induced hepatocellular carcinoma in rats. Environ ToxicolPharmacol. 2019; 72:103240.https://doi.org/10.1016/j.etap.2019.103240
  • Samaha MM, Said E, Salem HA. A comparative study of the role of crocin and sitagliptin in attenuation of STZ-induced diabetes mellitus and the associated inflammatory and apoptotic changes in pancreatic β-islets. Environ ToxicolPharmacol. 2019; 72:103238.https://doi.org/10.1016/j.etap.2019.103238
  • Samaha MM, Said E, Salem HA. Nilotinib enhances β-islets integrity and secretory functions in a rat model of STZ-induced diabetes mellitus. Eur J Pharmacol. 2019; 860:172569. https://doi.org/10.1016/j.ejphar.2019.172569
  • Mostafa ME, Shaaban AA, Salem HA. Dimethylfumarate ameliorates hepatic injury and fibrosis induced by carbon tetrachloride. ChemBiol Interact. 2019; 302:53-60. https://doi.org/10.1016/j.cbi.2019.01.029.
  • El-Kashef DH, Shaaban AA, El-Agamy DS. Protective role of pirfenidone against experimentally-induced pancreatitis. Pharmacol Rep. 2019; 71(5):774-781. https://doi.org/10.3390/molecules25112493
  • Ibrahim SRM, Ahmed N, Almalki S, Alharbi N, El-Agamy DS, Alahmadi LA, Saubr MK, Elkablawy M, Elshafie RM, Mohamed GA, El-Kholy MA. Vitexagnus-castus safeguards the lung against lipopolysaccharide-induced toxicity in mice. J Food Biochem. 2019; 43(3):e12750. https://doi.org/10.1111/jfbc.12750
  • El-Agamy DS, Ibrahim SRM, Ahmed N, Khoshhal S, Abo-Haded HM, Elkablawy MA, Aljuhani N, Mohamed GA. Aspernolide F, as a new cardioprotectivebutyrolactone against doxorubicin-induced cardiotoxicity. IntImmunopharmacol. 2019; 72:429-436.  http://dx.doi.org/10.3390/plants9111620
  • Abdel-Rahman N, Sharawy MH, Megahed N, El-Awady MS. Vitamin D3 abates BDL-induced cholestasis and fibrosis in rats via regulating Hedgehog pathway. ToxicolApplPharmacol. 2019; 380:114697.   https://doi.org/10.1016/j.taap.2019.114697
  • Makled MN, Sharawy MH, El-Awady MS. The dual PPAR-α/γ agonist saroglitazar ameliorates thioacetamide-induced liver fibrosis in rats through regulating leptin. NaunynSchmiedebergs Arch Pharmacol. 2019; 392, 1569–1576. https://doi.org/10.1007/s00210-019-01703-5
  • Keefe JA, Hwang SJ, Huan T, Mendelson M, Yao C, Courchesne P, Saleh MA, Madhur MS, Levy D. Evidence for a Causal Role of the SH2B3-β2M Axis in Blood Pressure Regulation. Hypertension. 2019; 73(2):497-503. https://doi.org/10.1161/HYPERTENSIONAHA.118.12094
  • Elmarakby AA, Ibrahim AS, Katary MA, Elsherbiny NM, El-Shafey M, Abd-Elrazik AM, Abdelsayed RA, Maddipati KR, Al-Shabrawey M. A dual role of 12/15-lipoxygenase in LPS-induced acute renal inflammation and injury. BiochimBiophysActaMol Cell Biol Lipids. 2019; 1864(11):1669-1680. https://doi.org/10.1016/j.bbalip.2019.07.009.
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  • Elmarakby A, Faulkner J, Pati P, Rudic RD, Bergson C. Increased arterial pressure in mice with overexpression of the ADHD candidate gene calcyon in forebrain. PLoS One. 2019; 14(2):e0211903. https://doi.org/10.1371/journal.pone.0211903.
  • Elshal M, Abu-Elsaad N, El-Karef A, Ibrahim T. Retinoic acid modulates IL-4, IL-10 and MCP-1 pathways in immune mediated hepatitis and interrupts CD4+ T cells infiltration. IntImmunopharmacol. 2019; 75:105808. https://doi.org/10.1016/j.intimp.2019.105808.
  • Abu-Elsaad N, El-Karef A. Protection against nonalcoholic steatohepatitis through targeting IL-18 and IL-1alpha by luteolin. Pharmacol Rep. 2019; 71(4):688-694. https://doi.org/10.1016/j.pharep.2019.03.009.
  • Shafeek F, Abu-Elsaad N, El-Karef A, Ibrahim T Gum Acacia mitigates diclofenac nephrotoxicity by targeting monocyte chemoattractant protein-1, complement receptor-1 and pro-apoptotic pathways. Food ChemToxicol. 2019; 129:162-168. https://doi.org/10.1016/j.fct.2019.04.050.
  • Oraby MA, El-Yamany MF, Safar MM, Assaf N, Ghoneim HA. Amelioration of Early Markers of Diabetic Nephropathy by Linagliptin in Fructose-Streptozotocin-Induced Type 2 Diabetic Rats. Nephron. 2019; 141(4):273-286. https://doi.org/10.1159/000495517.
  • Oraby MA, El-Yamany MF, Safar MM, Assaf N, Ghoneim HA. Dapagliflozin attenuates early markers of diabetic nephropathy in fructose-streptozotocin-induced diabetes in rats. Biomed Pharmacother. 2019; 109:910-920. https://doi.org/10.1016/j.biopha.2018.10.100.
  • Helal MG, Said E. Carvedilol attenuates experimentally induced silicosis in rats via modulation of P-AKT/mTOR/TGFβ1 signaling. IntImmunopharmacol. 2019; 70:47-55. https://doi.org/10.1016/j.intimp.2019.02.011.
  • Abdelrahman RS, Abdel-Rahman N Dimethyl fumarate ameliorates acetaminophen-induced hepatic injury in mice dependent of Nrf-2/HO-1 pathway. Life Sci. 2019; 217:251-260. https://doi.org/10.1016/j.lfs.2018.12.013.
  • El-Kerdawy MM, Ghaly MA, Darwish SA, Abdel-Aziz HA, Elsheakh AR, Abdelrahman RS, Hassan GS. New benzimidazothiazole derivatives as anti-inflammatory, antitumor active agents: Synthesis, in-vitro and in-vivo screening and molecular modeling studies. Bioorg Chem. 2019; 83:250-261. https://doi.org/10.1016/j.bioorg.2018.10.048.
  • El-Sharief MAMS, Abbas SY, El-Sharief AMS, Sabry NM, Moussa Z, El-Messery SM, Elsheakh AR, Hassan GS, El Sayed MT. 5-Thioxoimidazolidine-2-one derivatives: Synthesis, anti-inflammatory activity, analgesic activity, COX inhibition assay and molecular modelling study. Bioorg Chem. 2019; 87:679-687. https://doi.org/10.1016/j.bioorg.2019.03.075.
  • El-Kashef DH, El-Sheakh AR Hepatoprotective effect of celecoxib against tamoxifen-induced liver injury via inhibiting ASK-1/JNK pathway in female rats. Life Sci. 2019; 231:116573. https://doi.org/10.1016/j.lfs.2019.116573.
  • El-Kashef DH, Serrya MS. Sitagliptin ameliorates thioacetamide-induced acute liver injury via modulating TLR4/NF-KB signaling pathway in mice. Life Sci. 2019; 228:266-273. https://doi.org/10.1016/j.lfs.2019.05.019.
  • Elshaer SL, Alwhaibi A, Mohamed R, Lemtalsi T, Coucha M, Longo FM, El-Remessy AB. Modulation of the p75 neurotrophin receptor using LM11A-31 prevents diabetes-induced retinal vascular permeability in mice via inhibition of inflammation and the RhoA kinase pathway. Diabetologia. 2019; 62(8):1488-1500. https://doi.org/10.1007/s00125-019-4885-2.
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  • Periasamy R, Elshaer SL, Gangaraju R. CD140b (PDGFRβ) signaling in adipose-derived stem cells mediates angiogenic behavior of retinal endothelial cells. RegenEngTransl Med. 2019; 5(1):1-9. https://doi.org/10.1007/s40883-018-0068-9
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  • Marwa S. Zaghloul, Rehab S. Abdelrahman. Nilotinib ameliorates folic acid-induced acute kidney injury through modulation of TWEAK and HSP-70 pathways. Toxicology. 2019; 427:152303.         https://doi.org/10.1016/j.tox.2019.152303
  • Katary, M.A., Abdelsayed, R., Alhashim, A., Abdelhasib, M., Elmarakby, A.A. Salvianolic acid B slows the progression of breast cancer cell growth via enhancement of apoptosis and reduction of oxidative stress, inflammation, and angiogenesis. Int J Mol Sci. 2019; 20(22). https://doi.org/10.3390/ijms20225653
  • Jeong JH, Lee N, Tucker MA, Rodriguez-Miguelez P, Looney J, Thomas J, Derella CC, El-Marakby A, Musall JB, Sullivan JC, McKie KT, Forseen C, Davison GW, Harris RA. Tetrahydrobiopterin improves endothelial function in patients with cystic fibrosis. J ApplPhysiol (1985). 2019; 126(1):60-66. https://doi.org/10.1152/japplphysiol.00629.2018
  • Helal MG, Megahed NA, AbdElhameed AG. Saxagliptin mitigates airway inflammation in a mouse model of acute asthma via modulation of NF-kB and TLR4. Life Sci. 2019; 239:117017. https://doi.org/10.1016/j.lfs.2019.117017.

مواقع ذات صلة

خريطة الوصول

بيانات الاتصال

شارع الجمهورية - المنصورة - محافظة الدقهلية

 2246253 050

  vice.dean-pharmacy@mans.edu.eg

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