- Abdelmageed ME, Shehatou GS, Abdelsalam RA, Suddek GM, Salem HA. Cinnamaldehyde ameliorates STZ-induced rat diabetes through modulation of IRS1/PI3K/AKT2 pathway and AGEs/RAGE interaction. Naunyn-Schmiedebergs Archives of Pharmacology. 2019; 392(2):243-258. https://doi.org/10.1007/s00210-018-1583-4
- Heikal MM1, Shaaban AA, Elkashef WF, Ibrahim TM. Effect of febuxostat on biochemical parameters of hyperlipidemia induced by a high-fat diet in rabbits. Can J Physiol Pharmacol. 2019; 97(7):611-622. https://doi.org/10.1139/cjpp-2018-0731
- El-Sonbaty YA, Suddek GM, Megahed N, Gameil NM. Protocatechuic acid exhibits hepatoprotective, vasculoprotective, antioxidant and insulin-like effects in dexamethasone-induced insulin-resistant rats. Biochimie. 2019. pii: S0300-9084(19)30269-X. https://doi.org/10.1016/j.biochi.2019.09.011
- Abdel-Dayem MA, Shaker ME, Gameil NM. Impact of interferon β-1b, interferon β-1a and fingolimod therapies on serum interleukins-22, 32α and 34 concentrations in patients with relapsing-remitting multiple sclerosis. J Neuroimmunol. 2019; 337:577062. https://www.sciencedirect.com/science/article/pii/S0165572819301845
- Shawky NM, Shehatou GSG, Suddek GM, Gameil NM. Comparison of the effects of sulforaphane and pioglitazone on insulin resistance and associated dyslipidemia, hepatosteatosis, and endothelial dysfunction in fructose-fed rats. Environ ToxicolPharmacol. 2019; 66:43-54. https://doi.org/10.1016/j.etap.2018.12.008
- Khodir AE, Said E, Atif H, ElKashef HA, Salem HA. Targeting Nrf2/HO-1 signaling by crocin: Role in attenuation of AA-induced ulcerative colitis in rats. Biomed Pharmacother. 2019; 110:389-399. https://doi.org/10.1016/j.biopha.2018.11.133
- Zaghloul MS, Said E, Suddek GM, Salem HA. Crocin attenuates lung inflammation and pulmonary vascular dysfunction in a rat model of bleomycin-induced pulmonary fibrosis. Life Sci. 2019; 235:116794. https://doi.org/10.1016/j.lfs.2019.116794
- Nazmy EA, El-Khouly OA, Zaki MMA, Elsherbiny NM, Said E, Al-Gayyar MMH, Salem HA. Targeting p53/TRAIL/caspase-8 signaling by adiponectin reverses thioacetamide-induced hepatocellular carcinoma in rats. Environ ToxicolPharmacol. 2019; 72:103240.https://doi.org/10.1016/j.etap.2019.103240
- Samaha MM, Said E, Salem HA. A comparative study of the role of crocin and sitagliptin in attenuation of STZ-induced diabetes mellitus and the associated inflammatory and apoptotic changes in pancreatic β-islets. Environ ToxicolPharmacol. 2019; 72:103238.https://doi.org/10.1016/j.etap.2019.103238
- Samaha MM, Said E, Salem HA. Nilotinib enhances β-islets integrity and secretory functions in a rat model of STZ-induced diabetes mellitus. Eur J Pharmacol. 2019; 860:172569. https://doi.org/10.1016/j.ejphar.2019.172569
- Mostafa ME, Shaaban AA, Salem HA. Dimethylfumarate ameliorates hepatic injury and fibrosis induced by carbon tetrachloride. ChemBiol Interact. 2019; 302:53-60. https://doi.org/10.1016/j.cbi.2019.01.029.
- El-Kashef DH, Shaaban AA, El-Agamy DS. Protective role of pirfenidone against experimentally-induced pancreatitis. Pharmacol Rep. 2019; 71(5):774-781. https://doi.org/10.3390/molecules25112493
- Ibrahim SRM, Ahmed N, Almalki S, Alharbi N, El-Agamy DS, Alahmadi LA, Saubr MK, Elkablawy M, Elshafie RM, Mohamed GA, El-Kholy MA. Vitexagnus-castus safeguards the lung against lipopolysaccharide-induced toxicity in mice. J Food Biochem. 2019; 43(3):e12750. https://doi.org/10.1111/jfbc.12750
- El-Agamy DS, Ibrahim SRM, Ahmed N, Khoshhal S, Abo-Haded HM, Elkablawy MA, Aljuhani N, Mohamed GA. Aspernolide F, as a new cardioprotectivebutyrolactone against doxorubicin-induced cardiotoxicity. IntImmunopharmacol. 2019; 72:429-436. http://dx.doi.org/10.3390/plants9111620
- Abdel-Rahman N, Sharawy MH, Megahed N, El-Awady MS. Vitamin D3 abates BDL-induced cholestasis and fibrosis in rats via regulating Hedgehog pathway. ToxicolApplPharmacol. 2019; 380:114697. https://doi.org/10.1016/j.taap.2019.114697
- Makled MN, Sharawy MH, El-Awady MS. The dual PPAR-α/γ agonist saroglitazar ameliorates thioacetamide-induced liver fibrosis in rats through regulating leptin. NaunynSchmiedebergs Arch Pharmacol. 2019; 392, 1569–1576. https://doi.org/10.1007/s00210-019-01703-5
- Keefe JA, Hwang SJ, Huan T, Mendelson M, Yao C, Courchesne P, Saleh MA, Madhur MS, Levy D. Evidence for a Causal Role of the SH2B3-β2M Axis in Blood Pressure Regulation. Hypertension. 2019; 73(2):497-503. https://doi.org/10.1161/HYPERTENSIONAHA.118.12094
- Elmarakby AA, Ibrahim AS, Katary MA, Elsherbiny NM, El-Shafey M, Abd-Elrazik AM, Abdelsayed RA, Maddipati KR, Al-Shabrawey M. A dual role of 12/15-lipoxygenase in LPS-induced acute renal inflammation and injury. BiochimBiophysActaMol Cell Biol Lipids. 2019; 1864(11):1669-1680. https://doi.org/10.1016/j.bbalip.2019.07.009.
-
- Elmarakby A, Faulkner J, Pati P, Rudic RD, Bergson C. Increased arterial pressure in mice with overexpression of the ADHD candidate gene calcyon in forebrain. PLoS One. 2019; 14(2):e0211903. https://doi.org/10.1371/journal.pone.0211903.
- Elshal M, Abu-Elsaad N, El-Karef A, Ibrahim T. Retinoic acid modulates IL-4, IL-10 and MCP-1 pathways in immune mediated hepatitis and interrupts CD4+ T cells infiltration. IntImmunopharmacol. 2019; 75:105808. https://doi.org/10.1016/j.intimp.2019.105808.
- Abu-Elsaad N, El-Karef A. Protection against nonalcoholic steatohepatitis through targeting IL-18 and IL-1alpha by luteolin. Pharmacol Rep. 2019; 71(4):688-694. https://doi.org/10.1016/j.pharep.2019.03.009.
- Shafeek F, Abu-Elsaad N, El-Karef A, Ibrahim T Gum Acacia mitigates diclofenac nephrotoxicity by targeting monocyte chemoattractant protein-1, complement receptor-1 and pro-apoptotic pathways. Food ChemToxicol. 2019; 129:162-168. https://doi.org/10.1016/j.fct.2019.04.050.
- Oraby MA, El-Yamany MF, Safar MM, Assaf N, Ghoneim HA. Amelioration of Early Markers of Diabetic Nephropathy by Linagliptin in Fructose-Streptozotocin-Induced Type 2 Diabetic Rats. Nephron. 2019; 141(4):273-286. https://doi.org/10.1159/000495517.
- Oraby MA, El-Yamany MF, Safar MM, Assaf N, Ghoneim HA. Dapagliflozin attenuates early markers of diabetic nephropathy in fructose-streptozotocin-induced diabetes in rats. Biomed Pharmacother. 2019; 109:910-920. https://doi.org/10.1016/j.biopha.2018.10.100.
- Helal MG, Said E. Carvedilol attenuates experimentally induced silicosis in rats via modulation of P-AKT/mTOR/TGFβ1 signaling. IntImmunopharmacol. 2019; 70:47-55. https://doi.org/10.1016/j.intimp.2019.02.011.
- Abdelrahman RS, Abdel-Rahman N Dimethyl fumarate ameliorates acetaminophen-induced hepatic injury in mice dependent of Nrf-2/HO-1 pathway. Life Sci. 2019; 217:251-260. https://doi.org/10.1016/j.lfs.2018.12.013.
- El-Kerdawy MM, Ghaly MA, Darwish SA, Abdel-Aziz HA, Elsheakh AR, Abdelrahman RS, Hassan GS. New benzimidazothiazole derivatives as anti-inflammatory, antitumor active agents: Synthesis, in-vitro and in-vivo screening and molecular modeling studies. Bioorg Chem. 2019; 83:250-261. https://doi.org/10.1016/j.bioorg.2018.10.048.
- El-Sharief MAMS, Abbas SY, El-Sharief AMS, Sabry NM, Moussa Z, El-Messery SM, Elsheakh AR, Hassan GS, El Sayed MT. 5-Thioxoimidazolidine-2-one derivatives: Synthesis, anti-inflammatory activity, analgesic activity, COX inhibition assay and molecular modelling study. Bioorg Chem. 2019; 87:679-687. https://doi.org/10.1016/j.bioorg.2019.03.075.
- El-Kashef DH, El-Sheakh AR Hepatoprotective effect of celecoxib against tamoxifen-induced liver injury via inhibiting ASK-1/JNK pathway in female rats. Life Sci. 2019; 231:116573. https://doi.org/10.1016/j.lfs.2019.116573.
- El-Kashef DH, Serrya MS. Sitagliptin ameliorates thioacetamide-induced acute liver injury via modulating TLR4/NF-KB signaling pathway in mice. Life Sci. 2019; 228:266-273. https://doi.org/10.1016/j.lfs.2019.05.019.
- Elshaer SL, Alwhaibi A, Mohamed R, Lemtalsi T, Coucha M, Longo FM, El-Remessy AB. Modulation of the p75 neurotrophin receptor using LM11A-31 prevents diabetes-induced retinal vascular permeability in mice via inhibition of inflammation and the RhoA kinase pathway. Diabetologia. 2019; 62(8):1488-1500. https://doi.org/10.1007/s00125-019-4885-2.
-
- Periasamy R, Elshaer SL, Gangaraju R. CD140b (PDGFRβ) signaling in adipose-derived stem cells mediates angiogenic behavior of retinal endothelial cells. RegenEngTransl Med. 2019; 5(1):1-9. https://doi.org/10.1007/s40883-018-0068-9
-
- Marwa S. Zaghloul, Rehab S. Abdelrahman. Nilotinib ameliorates folic acid-induced acute kidney injury through modulation of TWEAK and HSP-70 pathways. Toxicology. 2019; 427:152303. https://doi.org/10.1016/j.tox.2019.152303
- Katary, M.A., Abdelsayed, R., Alhashim, A., Abdelhasib, M., Elmarakby, A.A. Salvianolic acid B slows the progression of breast cancer cell growth via enhancement of apoptosis and reduction of oxidative stress, inflammation, and angiogenesis. Int J Mol Sci. 2019; 20(22). https://doi.org/10.3390/ijms20225653
- Jeong JH, Lee N, Tucker MA, Rodriguez-Miguelez P, Looney J, Thomas J, Derella CC, El-Marakby A, Musall JB, Sullivan JC, McKie KT, Forseen C, Davison GW, Harris RA. Tetrahydrobiopterin improves endothelial function in patients with cystic fibrosis. J ApplPhysiol (1985). 2019; 126(1):60-66. https://doi.org/10.1152/japplphysiol.00629.2018
- Helal MG, Megahed NA, AbdElhameed AG. Saxagliptin mitigates airway inflammation in a mouse model of acute asthma via modulation of NF-kB and TLR4. Life Sci. 2019; 239:117017. https://doi.org/10.1016/j.lfs.2019.117017.
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